Many modern cancer treatments, including immunotherapy, depend on activating killer T cells to recognise and destroy tumours.

Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided ...

In the ever-evolving world of cell therapy, researchers often turn to T cells—a type of white blood cell—to transform the way we treat cancer. This is true for CAR T therapy, a modern cancer ...

Researchers found that lowering MHC I can expose cancerous or foreign cells to CD4+ T cell attack, reshaping assumptions ...

Analyzing nearly 6,000 MHC-1 complexes, the research team discovered patterns that can identify these preferences and predict immune responses across a broad range of human populations. The HLA ...

Within each individual’s immune system is a unique repertoire of billions of T cells patrolling the body to uncover and eliminate foreign threats. Yet this army is not foolproof and can miss the ...

Study introduces TRACeR-I, a protein platform with broad HLA compatibility, paving the way for advanced immune response engineering and disease-specific targeting. Study: Targeting peptide antigens ...