The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.
Cryo-electron microscopy (cryo-EM) is surpassing past limitations, now capturing near-atomic details of even the smallest protein–ligand complexes. AI-powered modeling and innovative imaging ...
The natural protein universe is vast, and yet, going beyond and designing new proteins not observed in nature can yield new functions and can solve problems in medicine or materials science. The past ...